Essay on Sickle Cell Lab - 1320 Words

Observations: When Malaria is present and infects red blood cells, parasites can infect cells carrying defective hemoglobin which may result in death. Allele frequency changes over time depending on the pressures or circumstances facing a particular population. African populations are especially impacted by both malaria and sickle cell anemia. Depending on the impacted population, allele frequency often shifts and well suited organisms are likely to survive and allele frequencies can increase. When a population is effected by disease or other circumstances, allele frequency may decrease or change. HbA (normal hemoglobin) and HbS (defective hemoglobin) have varying frequencies and while the HbS gene is present in populations it is†¦show more content†¦I will record this data and calculate the percentages so that my frequency for each HbA and HbS add up to 1. Predicted Results: If hypothesis 1 is true, and sickle cell allele frequency decreases and the HbA allele frequency increased And I test this hypothesis by picking red and white beans out of a sack at random in order to simulate and determine the HbS and HbA surviving allele frequencies Then the sickle cell allele frequency HbS will decrease and HbA frequency will increase. If hypothesis 2 is true and sickle cell allele frequency increases and HbA frequency decreases And I test this hypothesis by selecting red and white beans out of a sack at random in order to determine the HbS and HbA surviving allele frequencies Then the sickle cell allele frequency HbS will survive and have an increased frequency while HbA allele frequency will decrease. Data Tables: â€Å"Frequency of HbA† = 100 x [79/(79+15)] â€Å"Frequency of HbS† = 100 x [15/(15+79)] F1 Generation Surviving Alleles | Number of surviving HbA alleles | 79 | Number of surviving HbS alleles | 15 | F1 Generation Surviving Allele Frequency (added together these two figures must equal 100%) | Frequency (%) of HbA alleles | 84% | Frequency (%) of HbS alleles | 16% | F2 Generation Surviving Alleles | Number of surviving HbA alleles | 75 | Number of surviving HbS alleles | 11 | F2Show MoreRelatedThe Probability of Inheriting a Disease Is Not Random1816 Words   |  7 Pagesrate of Sickle Cell Anemia among people of African lineage. Sickle Cell disease is inherited and it affects the anatomy of the red blood cells, resulting in a sickle shape which then affects the functions of red blood cells causing a blood disorder. Sickle Cell is a recessive disease and persons affected have both copies of the hemoglobin S gene. 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